منابع مشابه
Drying of poloxamer hydrogel films.
The drying of hydrogel films formed by Poloxamer 407 poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) amphiphilic block copolymer was investigated at various air relative humidity (RH) conditions ranging from 11 to 97%. Initially, the amount of water lost increased linearly with the drying time. After this linear region (stage I), a nonlinear behavior was observed (stage II). The...
متن کاملMechanical, rheological and release behaviors of a poloxamer 407/ poloxamer 188/carbopol 940 thermosensitive composite hydrogel.
The aims of this study were to prepare a thermosensitive composite hydrogel (TCH) by mixing 24% (w/v) poloxamer 407 (P407), 16% (w/v) poloxamer 188 (P188) and 0.1% (w/v) carbopol 940 (C940), and to determine the effect of natural borneol/ (2-hydroxypropyl)-β-cyclodextrin (NB/HP-β-CD) inclusion complex on the phase transition temperature, mechanical, rheological properties, and release behaviors...
متن کاملDrying-induced cavitation in a constrained hydrogel.
Cavitation can be often observed in soft materials. Most previous studies were focused on cavitation in an elastomer, which is under different mechanical loadings. In this paper, we investigate cavitation in a constrained hydrogel induced by drying. Taking account of surface tension and chemo-mechanics of gels, we calculate the free energy of the system as a function of cavity size. The free en...
متن کاملDrying dip-coated colloidal films.
We present the results from a small-angle X-ray scattering (SAXS) study of lateral drying in thin films. The films, initially 10 μm thick, are cast by dip-coating a mica sheet in an aqueous silica dispersion (particle radius 8 nm, volume fraction ϕ(s) = 0.14). During evaporation, a drying front sweeps across the film. An X-ray beam is focused on a selected spot of the film, and SAXS patterns ar...
متن کاملCracking in drying latex films.
Thin films of latex dispersions containing particles of high glass transition temperature generally crack while drying under ambient conditions. Experiments with particles of varying radii focused on conditions for which capillary stresses normal to the film deform the particles elastically and generate tensile stresses in the plane of the film. Irrespective of the particle size, the drying fil...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Sciences
سال: 2004
ISSN: 0022-3549
DOI: 10.1002/jps.20021